Clinical Trials for Dogs with Cancer

Links last verified: August 20, 2026

Explore Current Research Trials in Canine Oncology

When a beloved dog is diagnosed with cancer, many families ask whether a clinical trial may provide an additional option. Canine oncology studies are conducted throughout the United States and around the world, but identifying an appropriate trial, and participating in one, can sometimes be challenging.

Each clinical trial has specific eligibility requirements.

These may include: 

  • A dog’s breed
  • Age
  • Weight
  • Overall health
  • Life expectancy
  • Cancer type
  • Cancer stage
  • Previous care
  • ...and other medical factors

Meeting a study’s general description does not guarantee acceptance. Pet parents should speak directly with the research team and their veterinary care provider to determine whether a trial may be appropriate for their dog.

It is also important to understand that clinical trials are not always free.

Research funding may cover only certain tests, medications, procedures, or appointments. Families may still be responsible for additional veterinary expenses, travel, lodging, and repeated visits over several weeks or months, especially when a study is located far from home.

The following links are intended to help pet parents and veterinary professionals find information about current canine oncology trials being conducted throughout the United States and, in some cases, internationally.

We encourage families to carefully review each study’s eligibility requirements, location, potential costs, time commitment, and possible benefits and risks with their veterinary team.

Search the AVMA Veterinary Clinical Trials Registry

Start Here: Nationwide Search Tools

If you are not sure where to begin, start with the AVMA registry. It lets you search by cancer type and by location, which is faster than checking individual centers one at a time.

AVMA Veterinary Clinical Trials Registry

The AVMA Veterinary Clinical Trials Registry, formerly known as the AVMA Animal Health Studies Database, helps dog parents and veterinary professionals find veterinary clinical studies taking place throughout the United States and Canada. By making this information easier to access, the registry supports continued research and progress in veterinary medicine and canine health care.

If you are interested in a clinical trial for your dog, begin by discussing the study and your dog’s potential eligibility with your veterinary care provider.

 

AVMA Clinical Trials

National Cancer Institute, Comparative Oncology Program

The Comparative Oncology Program develops and conducts clinical trials in partnership with veterinary teaching institutions throughout the United States. Dogs enrolled in these studies receive care from board-certified veterinary oncologists committed to improving comfort, quality of life, and cancer care for companion animals.

The knowledge gained through this research may help advance the understanding of cancer and support future progress in both canine and human oncology.

National Cancer Institute

PetCure Oncology

PetCure Oncology provides stereotactic radiation surgery and stereotactic radiation therapy, commonly known as SRS and SRT. These highly precise forms of radiation therapy have been used in human oncology and are now available for dogs with certain types of cancer.

PetCure Oncology reports using SRS and SRT in thousands of companion animals with a variety of tumor types. Its affiliated veterinary specialists continue to study these approaches to better understand their potential benefits, safety considerations, side effects, and appropriate applications in canine cancer care.

PetCure Oncology Clinical Trials

ACI Biosciences

Network conducting trials at participating private practices.

ACI Biosciences Clinical Trials

Northeast

Connecticut, Massachusetts, New Jersey, New York, Pennsylvania

University Programs

Specialty and Referral Practices

Mid-Atlantic and Southeast

Alabama, Florida, Georgia, Maryland, North Carolina, Virginia

University Programs

Midwest

Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Ohio, Wisconsin

University Programs

Mountain West and Southwest

Colorado, New Mexico

University Programs

Specialty and Referral Practices

West Coast

California, Oregon, Washington

University Programs

Specialty and Referral Practices

Canada

Ontario Veterinary College — Guelph, Ontario

Keep in Mind

Clinical trials may explore new approaches to diagnosing or supporting dogs with cancer. These may include chemotherapy, radiation therapy, surgical procedures, temperature-based therapies, immunotherapy, photodynamic therapy, and other emerging approaches.

Although many clinical trials take place at veterinary colleges and teaching hospitals, a growing number of specialty and referral practices also participate in canine cancer research. Some studies require every appointment to be completed at the participating institution, while others may allow certain tests, procedures, or follow-up visits to be handled by a dog’s regular veterinary team.

The words “experimental” and “investigational” can understandably feel concerning. Before a new therapy or procedure reaches a veterinary clinical trial, researchers have typically completed earlier stages of evaluation. However, unknowns may remain regarding its safety, effectiveness, or potential side effects. A study is offered because researchers believe the approach may provide meaningful benefits, but participation does not guarantee a positive outcome.

Pet parents should review the study’s purpose, requirements, possible benefits, known and unknown risks, costs, and available alternatives with the clinical trial team and their dog’s veterinary care provider before making a decision.